By motorway from Milan:
Take the A7 in the direction of Genoa (southwards); after Tortona turn into the connection reaching the A26 (Alessandria-Voltri) and then the A10 in the direction of Ventimiglia (westwards). Exit Imperia Est

By motorway from Turin:

Take the A6 in the direction of Savona (southwards) then the A10 in the direction of Ventimiglia (westwards). Exit  Imperia Est

By motorway from Genoa:

Take the A10 in the direction of Ventimiglia (westwards). Exit Imperia Est.

By motorway from Nice:
Take the A8(E74) in the direction of Ventimiglia (border) and Genoa (Gene).Exit Imperia Est

If you reach Imperia by train: line Genova-Ventimiglia. Station of Oneglia.